Frequency dependence of behavioral modulation by hippocampal electrical stimulation

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Frequency dependence of behavioral modulation by hippocampal electrical stimulation.

Electrical stimulation offers the potential to develop novel strategies for the treatment of refractory medial temporal lobe epilepsy. In particular, direct electrical stimulation of the hippocampus presents the opportunity to modulate pathological dynamics at the ictal focus, although the neuroanatomical substrate of this region renders it susceptible to altering cognition and affective proces...

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Frequency dependence of behavioral modulation by hippocampal electrical stimulation 2 ABBREVIATED TITLE : Behavioral modulation by hippocampal electrical stimulation

JOURNAL OF NEUROPHYSIOLOGY TITLE PAGE 1 TITLE: Frequency dependence of behavioral modulation by hippocampal electrical stimulation 2 ABBREVIATED TITLE: Behavioral modulation by hippocampal electrical stimulation 3 AUTHORS: Giorgio La Corte, Yina Wei, Nick Chernyy, Bruce J. Gluckman and Steven J. Schiff 4 1. Center for Neural Engineering, Department of Engineering Science and Mechanics, The Penn...

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Control of epileptic seizures by electrical low frequency deep brain stimulation: A review of probable mechanisms

Epilepsy is the most common neurological disease with no definitive method in treatment. Notably, the main way to treat and control epileptic seizures is drug therapy. However, about 20-30% of patients with epilepsy are drug resistant and require other therapeutic manners. Deep brain stimulation is a new therapeutic strategy for these patients. Conspicuously, there are no clear answers for basi...

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Biphasic modulation of hippocampal plasticity by behavioral stress and basolateral amygdala stimulation in the rat.

Explicit memory may depend on the hippocampus, whereas the amygdala may be part of an emotional memory system. Priming stimulation of the basolateral group of the amygdala (BLA) resulted in an enhanced long-term potentiation (LTP) in the dentate gyrus (DG) to perforant path (PP) stimulation 30, 90, 150, and 180 min after high-frequency stimulation (HFS). Exposure of rats to a behavioral stress ...

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Modulation of excitability by continuous low- and high-frequency stimulation in fully hippocampal kindled rats.

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ژورنال

عنوان ژورنال: Journal of Neurophysiology

سال: 2014

ISSN: 0022-3077,1522-1598

DOI: 10.1152/jn.00523.2013